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Annu Rev Pharmacol Toxicol 31, 25387

94 In the colonic mucosa of UC patients, one or more of the three ER stress pathways are activated, resulting in unbalanced protein synthesis and abnormal protein folding, which in turn exacerbates the inflammatory response and intestinal barrier disruption of UC

Transcription factor eb controls metabolic flexibility during exercise

For Asian populations, adapted protocols integrating core elements of the Mediterranean diet (high plant-based foods, healthy fats, fish) with local traditional ingredients can improve patient adherence